Table 3.

Univariate and multivariate analysis of factors associated with bladder recurrence

	Univariate			Multivariate model 1			Multivariate model 2
	HR	95% CI	P‐value	HR	95% CI	P‐value	HR	95% CI	P‐value
Age (≥ 73 vs ≤ 72)	0.6	0.2–1.3	0.223				0.4	0.2–1.1	0.085
pT stage
pT1 vs pTa	1.0	0.4–2.4	0.917
CIS
Positive vs negative	1.4	0.5–3.4	0.522
Number of tumors
Multiple vs solitary	3.1	1.3–8.2	0.010	2.8	1.2–7.5	0.020
Size
≥ 3 cm vs < 3 cm	2.0	0.6–5.4	0.250
EORTC (≥ 5 vs ≤ 4)	2.1	0.9–5.0	0.142				1.9	0.7–5.6	0.227
2nd TUR (yes vs no)	0.9	0.3–2.1	0.871
BCG (yes vs no)	0.9	0.3–2.2	0.873				0.4	0.1–1.1	0.064
TERT C228T in NMU‐positive vs urothelium‐negative	3.2	1.3–7.6	0.024	3.1	1.3–7.6	0.014	3.3	1.2–9.2	0.018