Table. Tumor Response by RECIST v1.1.
Characteristic | Cohort A1, dMMR endometrial cancer, No. (%) (n = 71) |
---|---|
Best overall response | |
Complete response | 9 (12.7) |
Partial response | 21 (29.6) |
Stable disease | 11 (15.5) |
Progressive disease | 27 (38.0) |
Not evaluable | 3 (4.2) |
Confirmed ORR | |
No. (%) [95% CI] | 30 (42.3) [30.6-54.6] |
Response ongoing | 25/30 (83.3) |
Disease control rate, No. (%) [95% CI] | 41 (57.7) [45.4-69.4] |
Duration of response, median (95% CI), mo | Not reached |
Abbreviations: dMMR, deficient mismatch mutation repair; ORR, objective response rate; RECIST v1.1, Response Evaluation Criteria in Solid Tumors version 1.1.