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. 2020 Aug 12;68(39):10456–10488. doi: 10.1021/acs.jafc.0c02894

Table 4. Overview of Greenhouse and Field Studies Conducted on HILsa.

    greenhouse studies
field studies
 
anion cation amount of AI applied (g/ha) fresh weight reductionb amount of AI applied (g/ha) herbicidal activity ref
MCPA tebuconazole 170 common lambsquarters, 17%; white mustard, 45% 170 cornflower, 0–38%; shepherd’s purse, 46–51% (40)
MCPA propiconazole 170 common lambsquarters, 31%; white mustard, 41% c   (40)
MCPA tetraalkylammonium c   200–500 field pennycress, 75–100%; larkspur, 54–93%; mayweed, 40–78%; rapeseed, 86–100% (16)
    400 common lambsquarters, 51–82%; flixweed, 69–80% 400 common lambsquarters, ∼95–99%; field pennycress, ∼82–99%  
MCPA alkylcyclohexyl- dimethylammonium 400 common lambsquarters, ∼21–47%; cornflower, ∼3%–76%; rapeseed, ∼1%−38%; white mustard, ∼19–58% c   (55)
MCPA 2-chloroethyl-trimethylammonium c     field pansy, field pennycress and rapeseed, results similar to the mixture of MCPA-salt and CCC (16)
    300 common lambsquarters, 10–75% 900 (MCPA-salt), 1450 (CCC) cornflower, 83–88%; rapeseed, 85–86%; scentless chamomile, 49–67% (56)
MCPA alkyl[2-(2-hydroxyethoxy)-ethyl]dimethylammonium 400 common lambsquarters, 41–60%; cornflower, 40–86%; rapeseed, 14–63% c   (58)
MCPA quaternary ammonium derivatives of d-glucose 400 cornflower, 39–69%; white mustard, 54–87% c   (59)
MCPA alkylbis(n-ethoxylated) methylammonium 400 common lambsquarters, ∼39–50%; white mustard, ∼15–37% c   (60)
MCPA betainium 400 common lambsquarters, 21%; white mustard, 38% 400 common lambsquarters, 98%; rapeseed, 100% (61)
MCPA N-alkylbetainium 400 common lambsquarters, ∼90–95%; cornflower, ∼98–99%; rapeseed, ∼97–99% 400 common lambsquarters, ∼98–100%; rapeseed, 100% (45)
MCPA carnitinium 400 common lambsquarters, 34%; white mustard, 38% 400 common lambsquarters, 98%; rapeseed, 100% (61)
MCPA acetylcholine 400 rapeseed, 37.55% c   (62)
MCPA [2-(methacryloyloxy)-ethyl]trimethylammonium; [2-(acryloyloxy)-ethyl]trimethylammonium 400 white mustard’s efficacy compared to commercial formulation set as 100%; ∼101–108% c   (63)
MCPA dialkanoyloxyethyl-dimethylammonium 400 white mustard efficacy compared to commercial formulation set as 100%, ∼129% 400 common lambsquarters efficacy compared to commercial formulation set as 100%, ∼158% (63)
MCPA derivatives of phenoxy-2-acetoxyethyl-decyldimethylammonium 400 germination index of cornflower, 6.99–15.48%; shoot length, 16.33–27.00 cm; root length, 7.00–11.63 cm c   (21)
MCPA 1,1-dialkylpyrrolidinium 400 common lambsquarters, 53–67% c   (25)
MCPA quaternized DABCO 400 cornflower, ∼84–94%; rapeseed, 72–89% c   (37)
MCPA bis(ammonium) 400 common lambsquarters, 32–60%; white mustard, 33–55% c   (67)
MCPA bis(ammonium) derivatives of tebuconazole 400 common lambsquarters, 60–87%; rapeseed, 45–55% c   (68)
2,4-D tebuconazole 170 common lambsquarters, 10%; white mustard, 19% 170 cornflower, 0–38%; shepherd’s purse, 50–58% (40)
2,4-D propiconazole 170 common lambsquarters, 16%; white mustard, 34% c   (40)
2,4-D 1,4-dimethylpiperazinium 400 common amaranth, 73.03%; flixweed, 47.34% 400 common lambsquarters, ∼89.30% (41)
2,4-D tetraalkylammonium 400 cornflower, 80%, field poppy, 44%, flixweed, 51%, rapeseed, 12% 400 common lambsquarters, ∼98%; rapeseed, ∼95% (44)
2,4-D tetraalkylammonium 400 common lambsquarters, 33–42%; flixweed, 42–72% 400 common lambsquarters, ∼85–95%; field pennycress, ∼80–98% (47)
2,4-D tetraalkylammonium c   c   (48)
2,4-D tetraalkylammonium c   450 common lambsquarters, 85–100%; field pennycress, 81–100%; shepherd’s purse, 81–100% (46)
2,4-D tetraalkylammonium c   450 cornflower, 75–79%; field pennycress, 74–78%; field poppy, 73–79%; rapeseed, 80–82%; scentless chamomile, 56–57%; shepherd’s purse, 79–82% (52)
2,4-D 2-chloroethyl-trimethylammonium 400 Cornflower, 1.047%, field poppy, 4.630%, flixweed, 3.465%, rapeseed, 5.628% 400 common lambsquarters, ∼38%; rapeseed, ∼35% (44)
2,4-D 2-chloroethyl-trimethylammonium 220–440 (2,4-D), 158–316 (CCC) white mustard, 50–75% 450 common lambsquarters, 72–95%; cornflower, 94% (48)
2,4-D quaternary ammonium derivatives of d-glucose 400 cornflower, 23–66%; white mustard, 39–71% c   (59)
2,4-D alkylbis(n-ethoxylated) methylammonium 400 common lambsquarters, ∼40–59%; white mustard, ∼21–28% c   (60)
2,4-D alkylbis(n-ethoxylated) methylammonium 400 cornflower, 75%, field poppy, 37%, flixweed, 47%, rapeseed, 14% 400 common lambsquarters, ∼85–97%; rapeseed, ∼92–95% (44)
2,4-D alkylbis(n-ethoxylated) methylammonium c   450 common lambsquarters, 100%; cornflower,100% (46)
2,4-D alkylbis(n-ethoxylated) methylammonium c   450 cornflower, 71%; field pennycress, 77%; field poppy, 75%; scentless chamomile, 52%; shepherd’s purse, 79%; rapeseed, 82% (52)
2,4-D betainium 400 common lambsquarters, 27%; white mustard, 32% 400 common lambsquarters, 100%; rapeseed, 100% (61)
2,4-D N-alkylbetainium 400 common lambsquarters, ∼83–90%; cornflower, ∼99–100%; rapeseed, ∼84–97% 400 common lambsquarters, 100%; rapeseed, 100% (45)
2,4-D carnitinium 400 common lambsquarters, 7%; white mustard, 32% 400 common lambsquarters, 98%; rapeseed, 100% (61)
2,4-D acetylcholine 400 rapeseed, 21.12% c   (62)
2,4-D [2-(methacryloyloxy)-ethyl]trimethylammonium; [2-(acryloyloxy)-ethyl]trimethylammonium 400 white mustard efficacy compared to commercial formulation set as 100%, ∼72–87% c   (63)
2,4-D dialkanoyloxyethyl-dimethylammonium 400 white mustard efficacy compared to commercial formulation set as 100%, ∼108% 400 common lambsquarters efficacy compared to commercial formulation set as 100%, ∼154% (63)
2,4-D derivatives of phenoxy-2-acetoxyethyl-decyldimethylammonium 400 germination index of cornflower, 4.82–7.49% shoot length, 21.00–22.86 cm; root length, 4.14–6.33 cm c   (21)
2,4-D 1,1-dialkylpyrrolidinium 400 common lambsquarters, 54–59% c   (25)
2,4-D bis(ammonium) 400 common lambsquarters, 27–47%; white mustard, 47–52% c   (67)
2,4-D hexamethylene-1,6-bis(3-methylimidazolium) 400 flixweed, 77.15%; common amaranth, 93.57% 400 common lambsquarters, 96.78% (41)
MCPP tebuconazole 170 common lambsquarters, 21%; white mustard, 19% c   (40)
MCPP propiconazole 170 common lambsquarters, 24%; white mustard, 13% c   (40)
MCPP tetraalkylammonium 400 common lambsquarters, 38–68%; flixweed, 74–86% 400 common lambsquarters, ∼87–95%; field pennycress, ∼90–99% (47)
MCPP betainium 400 common lambsquarters, 22%; white mustard, 0% c   (61)
MCPP N-alkylbetainium 400 common lambsquarters, ∼50–55%; cornflower, ∼90–97%; rapeseed, ∼97–98% c   (45)
MCPP carnitinium 400 white mustard, 9%; common lambsquarters, 19% c   (61)
MCPP acetylcholine 400 rapeseed, 56.23% c   (62)
MCPP [2-(methacryloyloxy)-ethyl]trimethylammonium, [2-(acryloyloxy)-ethyl]trimethylammonium 400 white mustard efficacy compared to commercial formulation set as 100%, ∼88–93% c   (63)
MCPP dialkanoyloxyethyl-dimethylammonium 400 common lambsquarters efficacy compared to commercial formulation set as 100%, ∼120% 400 white mustard efficacy compared to commercial formulation set as 100%, ∼104% (63)
MCPP derivatives of phenoxy-2-acetoxyethyldecyl-dimethylammonium 400 germination index of cornflower, 0–23.45%; shoot length, 0.50–43.22 cm; root length, 0.50–15.67 cm c   (21)
MCPP 1,1-dialkylpyrrolidinium 400 common lambsquarters, 47–63% c   (25)
MCPP 1,1-dialkylpiperidinium 400 common lambsquarters, 63–85%; cornflower, 40–88%; white mustard, 50–98%; c   (66)
MCPP bis(ammonium) 400 common lambsquarters, 37–51%; white mustard, 8–22% c   (67)
dicamba [2-(2-hydroxyethoxy)ethyl]ammonium 200 common amaranth, ∼67%; common lambsquarters, ∼32%; cornflower, ∼83% c   (39)
dicamba bis(3-aminopropyl)ammonium 200 common amaranth, ∼73%; common lambsquarters, ∼35%; cornflower, ∼44% c   (39)
dicamba tebuconazole 200 common lambsquarters, 16%; white mustard, 23% c   (40)
dicamba propiconazole 200 common lambsquarters, 22%; white mustard, 26% c   (40)
dicamba (3-aminopropyl)bis(ammonium) 200 common amaranth, ∼82%; common lambsquarters, ∼41%; cornflower, ∼39% c   (39)
dicamba tetraalkylammonium 0.002–0.004 mol/L common lambsquarters, 41.7–45.7%; white mustard, 18.5–27.1% 200 common lambsquarters, 62.5–92%; cornflower, 95% (26)
dicamba tetraalkylammonium 200 common lambsquarters, 75–85%; flixweed, 43–75% 200 common lambsquarters, ∼97–99%; field pennycress, ∼75–99% (47)
dicamba alkyl[2-(2-hydroxyethoxy)-ethyl]dimethylammonium 200 common lambsquarters, 23.75–68.91%; cornflower, 65.40–84.88%; oilseed rape, 0.00–20.81% c   (58)
dicamba alkyl[2-(2-hydroxyethoxy)-ethyl]dimethylammonium 200 common amaranth, ∼79%; common lambsquarters, ∼37%; cornflower, ∼27% c   (39)
dicamba alkylbis(n-ethoxylated)-methylammonium c   200 common lambsquarters, 56.3–62.5% (26)
dicamba alkylbis(n-ethoxylated)-methylammonium 200 common amaranth, ∼63%; common lambsquarters, ∼68%; cornflower, ∼52% c   (39)
dicamba N-alkylbetainium 200 common lambsquarters, ∼90–92%; cornflower, ∼97–99%; rapeseed, ∼50–78% 200 common lambsquarters, ∼98%; rapeseed, ∼95% (45)
dicamba acetylcholine 200 rapeseed, −4.46% c   (62)
dicamba [2-(methacryloyloxy)-ethyl]trimethylammonium, [2-(acryloyloxy)-ethyl]trimethylammonium 200 white mustard efficacy compared to commercial formulation set as 100%, ∼101–112% 200 common lambsquarters efficacy compared to commercial formulation set as 100%, ∼80–120% (63)
dicamba derivatives of phenoxy-2-acetoxyethyldecyl-dimethylammonium 200 germination index of cornflower, 5.99–22.29%; shoot length, 12.33–21.75 cm; root length, 9.00–14.89 cm c   (21)
dicamba 4,4-dialkylmorpholinium c   200 common lambsquarters, 57.5% (26)
dicamba 4,4-dialkylmorpholinium c   c   (73)
dicamba 1,1-dialkylpiperidinium c   200 common lambsquarters, 62.5% (26)
dicamba 1-alkyl-4-hydroxy-1-methylpiperidinium 200 common amaranth, ∼70–90%; common lambsquarters, ∼54–59%; cornflower, ∼71–82% c   (39)
dicamba bis(ammonium) 200 common lambsquarters, 32–95%; cornflower, 54%; rapeseed, 54%; white mustard, 9–33% c   (67)
dicamba bis(ammonium) derivatives of tebuconazole 200 common lambsquarters, 58–85%; rapeseed, 10–38% c   (68)
2,4-DP tetraalkylammonium 300 common lambsquarters, ∼20–40%; cornflower, ∼25–77% c   (57)
2,4-DP alkylbis(n-ethoxylated)-methylammonium 300 common lambsquarters, ∼17%; cornflower, ∼58% c   (57)
2,4-DP acetylcholine 400 rapeseed, 36.28% c   (62)
2,4-DP 1,1-dialkylpiperidinium 400 common lambsquarters, 20–90%; cornflower, 20–60%; rapeseed, 20–91% c   (65)
4-CPA derivatives of phenoxy-2-acetoxyethyldecyl-dimethylammonium 400 germination index of cornflower, 5.32–19.46%; shoot length, 17.83–45.00 cm; root length, 5.33–14.63 cm c   (21)
4-CPA 1,1-dialkylpyrrolidinium 400 common lambsquarters, 53–65% c   (25)
clopyralid alkylammonium c   50, 100, and 200 creeping thistle, brachyotus sowthistle, Cephalanoplos setosum, 25.2–77.3% (27)
clopyralid derivatives of phenoxy-2-acetoxyethyldecyl-dimethylammonium   germination index of cornflower, 3.16–32.77%; shoot length, 7.50–17.00 cm; root length, 2.71–24.63 cm c   (21)
pelargonate tetraalkylammonium 2720 common lambsquarters, ∼18–50%; cornflower, 53%; rapeseed, ∼4–45%; white mustard, 33%; winter wheat, 29% c   (33)
pelargonate choline 2720 common lambsquarters, approx −28%; rapeseed, approx −4% c   (33)
pelargonate alkylbis(n-ethoxylated) methylammonium 2720 cornflower, 37%; rapeseed, ∼18%; white mustard, 16%; winter wheat, 5% c   (33)
pelargonate N-alkylbetainium 2720 common lambsquarters, ∼20% c   (33)
pelargonate acetylcholine 3000 rapeseed, 24.58% c   (62)
pelargonate dialkanoyloxyethyl-dimethylammonium 2720 rapeseed, ∼10% c   (33)
pelargonate quaternized DABCO 5440–8160 common lambsquarters, 36.60–93.48%; rapeseed, 20.70–95.93% c   (34)
bentazone 1-alkylpyridinium c   1000–3000 brachyotus sowthistle, common lambsquarters, creeping woodsorrel, ∼30–91% (24)
bromoxynil alkylammonium 90–360 common amaranth, ∼17–82% c   (23)
bromoxynil 1-alkylpyridinium 90–360 common amaranth, ∼20–84% c   (23)
clodinafop choline c     complete inhibition of weed grass after 15 days (8)
fomesafen tetraalkylammonium c Lack of data 45–180 creeping woodsorrel, annual fleabane herb, dandelion, ∼49–88% (32)
glyphosate tetraalkylammonium 22.5–720 cornflower, ∼8–88%; winter wheat, ∼10–84% 1180 couchgrass, 94–100% (31)
glyphosate tetraalkylammonium 180–360 common lambsquarters, 83–94%; cornflower, 19–90%; white mustard, 64–89% 1180 couchgrass regrowth from rhizome buds, 7–16% (31)
glyphosate alkylbis(n-ethoxylated) methylammonium 22.5–720 cornflower, ∼10–84%; winter wheat, ∼2–64% 1180 couchgrass, 99–100% (31)
glyphosate alkylbis(n-ethoxylated) methylammonium 180–360 common lambsquarters, 81–94%; cornflower, 17–88%; white mustard, 75–91%     (31)
glyphosate 4,4-dialkylmorpholinium 22.5–720 cornflower, ∼10–92%; winter wheat, ∼2–56% 1180 couchgrass, 20–99% (31)
glyphosate 4,4-dialkylmorpholinium 180–360 common lambsquarters, 54–68%; cornflower, 21–63%; white mustard, 11–81% 1180 couchgrass regrowth from rhizome buds, 26% (31)
iodosulfuron-methyl acetylcholine 7.5 rapeseed, 37.42% c   (62)
MCPB 1,1-dialkylpiperidinium 600 common lambsquarters, 71–88%; rapeseed, 70–95% c   (64)
mesotrione 1-alkylpyridinium c   50–200 common lambsquarters, common amaranth, field bindweed, field sowthistle, ∼20–98% (38)
metsulfuron-methyl tetraalkylphosphonium 4 common lambsquarters, 93–94%; rapeseed, 44–67% 8 chickweed, 100%; field forget-me-not, 100%; field pansy, 93–100%; field poppy, 74%; hemp nettle, 100%; mayweed, 95–100%; persian speedwell, 63%; shepherd’s purse, 96%; wild buckwheat, 97% (29)
metsulfuron-methyl 4,4-dialkylmorpholinium 4 common lambsquarters, 71%; rapeseed, 54% 8 chickweed, 100%; field forget-me-not, 96–100%; field pansy, 89–100%; field poppy, 68%; hemp nettle, 100%; mayweed, 89–99%; persian speedwell, 78%; shepherd’s purse, 96%; wild buckwheat, 97% (29)
metsulfuron-methyl 1,1-dialkylpiperidinium 4 common lambsquarters, 21%; rapeseed, 34% 8 chickweed, 99–100%; field forget-me-not, 87–100%; field pansy, 90–100%; field poppy, 85%; hemp nettle, 100%; mayweed, 92–100%; persian speedwell, 71%; shepherd’s purse, 94%; wild buckwheat, 95% (29)
metsulfuron-methyl 1,3-dialkylimidazolium 4 common lambsquarters, 67–80%; rapeseed, 26–60% 8 chickweed, 100%; field forget-me-not, 92–100%; field pansy, 85–100%; field poppy, 66–76%; hemp nettle, 100%; mayweed, 88–100%; persian speedwel, 66–76%; shepherd’s purse, 95–96%; wild buckwheat, 97% (29)
nicosulfuron tetraalkylammonium 0.5–20 mg/L common amaranth, 37.68–65.11% c   (30)
nicosulfuron choline 0.5–20 mg/L common amaranth, 46.73–61.73% c   (30)
nicosulfuron 1-alkylpyridinium 0.5–20 mg/L common amaranth, 59.4–81.43% 50–200 common lambsquarters, ∼22–90%; green bristlegrass, ∼23–92% (30)
MCPA/dicamba (oligomeric) alkylbis(n-ethoxylated) methylammonium c   267 (MCPA), 133 (dicamba) black bindweed, ∼59–92%; common lambsquarters, ∼98–100%; rapeseed, ∼95–98% (43)
MCPA/dicamba (oligomeric) alkylbis(n-ethoxylated) methylammonium c   300 (MCPA), 100 (dicamba) black bindweed, ∼62%; common lambsquarters, ∼98–99%; rapeseed, ∼65–100% (43)
MCPA/glyphosate (oligomeric) tetraalkylammonium 360 (glyphosate), 73.9 (MCPA) common amaranth, 95%; common lambsquarters, 66%; white mustard, 94%; winter wheat, 91% 360 (glyphosate), 73.9 (MCPA) cornflower, ∼98–100%; poppy field, ∼86–89%; winter wheat, ∼100% (42)
MCPA/glyphosate (oligomeric) alkylbis(n-ethoxylated) methylammonium 360 (glyphosate), 73.9 (MCPA) common amaranth, 96%; common lambsquarters, 68%; white mustard, 88%; winter wheat, 89% 360 (glyphosate), 73.9 (MCPA) cornflower, ∼96–99%; poppy field, ∼90–93%; winter wheat, ∼96–100% (42)
MCPA/dicamba (DSHIL) alkyl[2-(2-hydroxyethoxy)-ethyl]dimethylammonium 300 (MCPA), 40 (dicamba) common lambsquarters, 36.91–53.67%; cornflower, 45.47–85.30%; rapeseed, 6.54–51.63% c   (58)
MCPA/glyphosate (DSHIL) tetraalkylammonium 360 (glyphosate), 73.9 (MCPA) common amaranth, 91–96%; common lambsquarters, 45–70%; white mustard, 74–89%; winter wheat, 86–89% c   (42)
MCPA/glyphosate (DSHIL) alkylbis(n-ethoxylated)-methylammonium 360 (glyphosate), 73.9 (MCPA) common amaranth, 94%; common lambsquarters, 48%; white mustard, 88%; winter wheat, 89% 360 (glyphosate), 73.9 (MCPA) cornflower, ∼97–99%; poppy field, ∼72–88%; winter wheat, ∼88–97% (42)
dicamba/glyphosate (DSHIL) tetraalkylammonium 360 (glyphosate), 83.7 (dicamba) common amaranth, 96%; common lambsquarters, 68%; white mustard, 90%; winter wheat, 90% 360 (glyphosate), 73.9 (dicamba) cornflower, ∼92–96%; poppy field, ∼64–76%; winter wheat, ∼78–92% (42)
dicamba/glyphosate (DSHIL) tetraalkylphosphonium 360 (glyphosate), 83.7 (dicamba) common amaranth, 96%; common lambsquarters, 78%; white mustard, 84%; winter wheat, 93% 360 (glyphosate), 73.9 (dicamba) cornflower, ∼98–99%; poppy field, ∼95–99%; winter wheat, ∼90–98% (42)
dicamba/glyphosate (DSHIL) alkylbis(n-ethoxylated)-methylammonium 360 (glyphosate), 83.7 (dicamba) common amaranth, 92%; common lambsquarters, 59%; white mustard, 92%; winter wheat, 89% 360 (glyphosate), 73.9 (dicamba) cornflower, ∼87–94%; poppy field, ∼58–85%; winter wheat, ∼89–96% (42)
a

Table does not include salts with melting points greater than 100 °C.

b

Unless stated otherwise.

c

Not tested.