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. 2020 Oct 1;10:16314. doi: 10.1038/s41598-020-73253-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Viability and growth on various carbon sources in comparison to experimental reports. (A) Comparative analysis of in silico viability on multiple carbon sources and the reported data in MycoBank and other literature. (B) The in silico specific growth rate (h⁻¹) simulated by FBA of L. kluyveri on different carbon sources in both aerobic and anaerobic conditions. The error bars represent the maximum and minimum specific growth rate for flux variability analysis. (C) The correlation between the experimental growth rate and in silico growth rate on various carbon sources.