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. 2020 Oct 1;10:16240. doi: 10.1038/s41598-020-73448-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Abundance of Fusobacterium spp. and F. nucleatum in colorectal cancer patients. (A) Proportion of Fusobacterium spp. positivity in non-tumorous (N-CRC, n = 26) and tumorous colon tissues (T-CRC, n = 27). (B) Proportion of F. nucleatum in N-CRC (n = 26) and T-CRC (n = 27) tissues. (C) Correlation between Fusobacterium spp. and F. nucleatum in N- and T-CRC. (D) Correlation of Fusobacterium spp. abundance between N-CRC and T-CRC. (E) Correlation of F. nucleatum abundance between N-CRC and T-CRC. Data are presented as raw Ct-values; negative undetectable values were set to Ct of 40, CT-value > 38 were defined as negative and CT-value ≤ 38 were defined as positive. Fisher’s exact and Spearman’s tests were used for analyses.