Table 1.
Clinicopathological characteristics of Gastric Cancer patients in relation to F. nucleatum positivity.
| F. nucleatum | |||||||
|---|---|---|---|---|---|---|---|
| All | Positive | Negative | p | ||||
| n = 81 | % | n = 23 | % | n = 57 | % | ||
| Age | 65.85 | ± 11.58 | 70.04 | ± 9.70 | 64.16 | ± 12.19 | 0.042* |
| Gender | 0.21 | ||||||
| Male | 47 | 58 | 11 | 48 | 36 | 63 | |
| Female | 34 | 42 | 12 | 52 | 21 | 37 | |
| Tumor localization | 0.37 | ||||||
| Cardia | 8 | 10 | 4 | 17 | 4 | 7 | |
| Corpus | 45 | 56 | 12 | 52 | 32 | 56 | |
| Antrum | 28 | 34 | 7 | 30 | 21 | 37 | |
| UICC | 0.75 | ||||||
| I | 16 | 20 | 4 | 17 | 11 | 19 | |
| II | 21 | 26 | 8 | 35 | 13 | 23 | |
| III | 36 | 44 | 9 | 39 | 27 | 47 | |
| IV | 8 | 10 | 2 | 9 | 6 | 11 | |
| T | 0.77 | ||||||
| 1 + 2 | 18 | 22 | 4 | 17 | 13 | 23 | |
| 3 | 36 | 45 | 10 | 43 | 26 | 46 | |
| 4 | 27 | 33 | 9 | 39 | 18 | 32 | |
| N | 0.26 | ||||||
| 0 | 29 | 36 | 9 | 39 | 19 | 33 | |
| 1 | 15 | 19 | 6 | 26 | 9 | 16 | |
| 2 | 13 | 16 | 1 | 4 | 12 | 21 | |
| 3 | 23 | 28 | 6 | 26 | 17 | 30 | |
| Unknown | 1 | 1 | 1 | 4 | 0 | 0 | |
| M | 1 | ||||||
| 0 | 72 | 89 | 20 | 87 | 51 | 89 | |
| 1 | 8 | 10 | 2 | 9 | 6 | 11 | |
| Unknown | 1 | 1 | 1 | 4 | 0 | 0 | |
| Grading | 0.37 | ||||||
| 1 | 3 | 4 | 0 | 0 | 3 | 5 | |
| 2 | 29 | 36 | 10 | 43 | 18 | 32 | |
| 3 | 49 | 60 | 13 | 57 | 36 | 63 | |
| Laurén-classification | 0.61 | ||||||
| Diffuse Type | 44 | 54 | 12 | 52 | 32 | 56 | |
| Intestinal Type | 26 | 32 | 6 | 26 | 19 | 33 | |
| Mixed Type | 7 | 9 | 3 | 13 | 4 | 7 | |
| Unknown | 4 | 5 | 2 | 9 | 2 | 4 | |
| H. pylori | 0.82 | ||||||
| Negative | 8 | 10 | 2 | 9 | 6 | 11 | |
| Positive | 17 | 21 | 5 | 22 | 12 | 21 | |
| Unknown | 56 | 69 | 16 | 70 | 39 | 68 | |
F. nucleatum positivity was defined by the cut-off of ≤ 38. *Unpaired t-test. ns: non-significant. F. nucleatum data were available only for 80 subjects. UICC: Union for International Cancer Control; T-primary tumor stage; N- lymphnode metastasis staging; M: metastasis staging.