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Mmp12 gene expression and protein are upregulated in BAL cells of MWCNT-instilled C57BL/6. (A) Mmp12 gene expression is increased at 3 days, with a peak at 10 days, and remains significantly upregulated at 60 days post MWCNT-instillation (p ≤ 0.05; n ≥ 3 per group). (B) Immunofluorescent anti-MMP12 staining was minimal at 3 days, with a peak at 10 days and persistence through 60 days (representative of n = 3).
