Table 1.
General characteristics of the study population
| N = 1420 | |
|---|---|
| Age, years | 79.5 (77.0–83.0) |
| Women | 804 (56.6%) |
| Living alone | 337 (23.7%) |
| Education, years | 11.0 (8.0–14.0) |
| ADL score | 0.0 (0.0–1.0) |
| ADL dependent | 55 (3.9%) |
| IADL score | 2.0 (0.0–8.0) |
| IADL dependent | 590 (41.5%) |
| MMSE score | 29.0 (27.0–30.0) |
| MMSE < 24 | 104 (7.3%) |
| GDS score | 2.0 (1.0–4.0) |
| GDS > 5 | 170 (12.0%) |
| CIRS-G total score | 7.0 (5.0–11.0) |
| CIRS-G severity index | 1.5 (1.2–1.8) |
| Number of current medications | 6.0 (4.0–9.0) |
| Creatinine, mg/dl | 0.93 (0.78–1.21) |
| BIS eGFR, ml/min/1.73 m2 | 56.4 (45.8–64.8) |
| ≥ 90 | 9 (0.6%) |
| 60–89 | 538 (37.9%) |
| 45–59 | 542 (38.2%) |
| 30–44 | 259 (18.2%) |
| 15–29 | 72 (5.1%) |
| ≥ 60 | 547 (38.5%) |
| < 60 | 873 (61.5%) |
| CKD-EPI eGFR, ml/min/1.73 m2 | 68.4 (52.6–80.7) |
| ≥ 90 | 42 (3.0%) |
| 60–89 | 884 (62.3%) |
| 45–59 | 247 (17.4%) |
| 30–44 | 163 (11.5%) |
| 15–29 | 84 (5.9%) |
| ≥ 60 | 926 (65.2%) |
| < 60 | 494 (34.8%) |
| FAS eGFR, ml/min/1.73 m2 | 56.8 (44.7–66.5) |
| ≥ 90 | 26 (1.8%) |
| 60–89 | 553 (38.9%) |
| 45–59 | 480 (33.8%) |
| 30–44 | 253 (17.8%) |
| 15–29 | 108 (7.6%) |
| ≥ 60 | 579 (40.8%) |
| < 60 | 841 (59.2%) |
| ACR, mg/g | 12.6 (4.7–32.8) |
| < 30 | 1037 (73.0%) |
| 30–300 | 288 (20.3%) |
| > 300 | 95 (6.7%) |
| Anthropometric measurements | |
| height, cm | 162.0 (156.0–170.0) |
| weight, kg | 72.0 (62.7–82.0) |
| BMI, kg/m2 | 27.0 (24.4–30.0) |
| BIA parameters | |
| FFM, percentage | 69.0 (62.9–75.0) |
| FFM, kg | 48.5 (42.6–57.5) |
| FFMI, kg/m2 | 18.5 (17.1–20.2) |
| FM, percentage | 31.0 (24.9–37.1) |
| FM, kg | 21.9 (16.7–28.6) |
| FMI, kg/m2 | 8.3 (6.3–10.9) |
| ASM, percentage | 0.25 (0.23–0.28) |
| ASM, kg | 18.1 (15.2–21.7) |
| ASMI, kg/m2 | 6.9 (6.2–7.6) |
| Grip strength, kg | 24.0 (18.0–31.0) |
| SPPB score | 10.0 (8.0–11.0) |
Note: continuous variables are expressed as median and interquartile difference. Abbreviations ACR Albumin-to-creatinine ratio, ADL Activities of daily living, ASM Appendicular skeletal muscle mass, ASMI Appendicular skeletal muscle mass index, BIA Bioelectrical impedance analysis, BIS Berlin Initiative Study, BMI Body mass index, CIRS-G Cumulative illness rating scale for geriatrics, CKD-EPI Chronic Kidney Disease Epidemiological Collaboration, eGFR Estimated glomerular filtration rate, FAS Full Age Spectrum, FFM Fat-free mass, FFMI Fat-free mass index, FM Fat mass, FMI Fat mass index, GDS Geriatric depression scale, IADL Instrumental activities of daily living, MMSE Mini mental state examination, SSPB Short physical performance battery