Table 1.
Demographic and clinical data.
| MS patients | OND patients | ||||
|---|---|---|---|---|---|
| All MS n = 42 | CIS n = 23 | RRMS n = 19 | n = 23 | ||
| Gender, males:females, (n:n) | 13:29 | 8:15 | 5:14 | 8:15 | |
| Age at sampling, years (mean ± SD) | 38.3 ± 11.7 n = 42 | 37.7 ± 12.6 | 39.1 ± 10.7 | 39.2 ± 13.1 | |
| MS disease duration, months [median (P25, P75)] | 7 (1.8, 28) n = 42 | 2 (1, 8) | 17 (7, 79) | ||
| EDSS at sample collection [median (P25, P75)] | 1 (0, 2) n = 38 | 1 (1, 0.5) | 1.5 (0.8, 2.1) | ||
| MSSS prior to treatment [median (P25, P75)] | 2.7 (0.7, 5.2) n = 22 | 1.6 (0.6, 4.8) | 3 (0.6, 5.2) | ||
| Number of relapses at sample collection [median (P25,P75)] | 1 (1, 2) n = 42 | 1 (1, 1) | 2 (2, 3) | ||
| Annual rate of relapses prior to treatment [median (P25,P75)] | 1.2 (0.4, 3.3) n = 42 | 1.1 (0.4, 4.4) | 1.2 (0.3, 2.5) | ||
| Period of time: last relapse - sample collection, months [median (P25,P75)] | 2.5 (0.75, 6) n = 42 | 2 (1, 8) | 3 (0, 5) | ||
| Radiological measurements | Number of gadolinium enhancing lesions [median (P25,P75)] | 1 (0, 3) n = 28 | 0 (0, 2) | 1 (0, 3) | |
| Percentage of patients with more than 10 T2 lesions (%) | 83 n = 41 | 91.3 | 72.2 | ||
CIS, clinically isolated syndrome; EDSS, Expanded Disability Status Scale; MS, multiple sclerosis; MSSS, Multiple Sclerosis Severity Scale; n, number of subjects; OND, other neurological diseases; P25, 25th percentile, P75, 75th percentile; RRMS, relapsing-remitting MS; SD, standard deviation.