Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Conditioned pain modulation paradigm. Test stimulus (TS): stimulus-response function of painful pressure at left leg. Conditioned stimulus (CS): 10°C cold water immersion of the right hand for 1 min. Pain was rated after 45 s of the CS on a VAS ranging from 0 = no pain to 100 = unbearable pain. Sequence of consecutive applied stimuli: first test stimulus (TS1), CS, second test stimulus (TS2).
