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Comparison of PfHsp70-x SBD with homologues. Shown here is a structural superposition of PfHsp70-x SBD (blue) with the equivalent domains of human Hsp70 (red; PDB entry 4po2; Zhang et al., 2014 ▸) and E. coli DnaK (wheat; PDB entry 1dkz; Zhu et al., 1996 ▸). PfHsp70-x SBD is substantially similar to both of these domains; however, it is structurally closer to the human chaperone than to the prokaryotic counterpart.
