Table 1.
Summary of similar published studies
| Reference | Age (y) | Sex | Ethnicity | Chief complaint/s | Therapy | Outcome |
|---|---|---|---|---|---|---|
| Kannan et al. [7] (2019) | 13 | Male | Indian | Sudden vision loss | - Oral steroids at 1 mkd | Loss of vision |
| - Oral methotrexate 10 mg/week | ||||||
| - Bevacizumab for 3 doses | ||||||
| Anguita et al. [8] (2019) | 12 | Female | Peruvian | Headache Amaurosis fugax, oculus sinister Right hemiparesis Bradylalia |
- Steroids | Partial reperfusion of carotids and good perfusion of both eyes |
| - Mycophenolate mofetil | ||||||
| Malik et al. [9] (2015) | 35 | Female | Pakistani | Gradual loss of vision in both eyes | - Oral dexamethasone 60 mg daily | Loss of vision |
| Shailaja et al. [10] (2013) | 22 | Female | Indian | Gradual loss of vision in both eyes and chronic pain in both eyes | - Systemic steroids at 1 mkd | Sudden cardiac death |
| Sakthiswary et al. [11] (2012) | 20 | Female | Malaysian | Loss of vision in both eyes, fatigue, and headache | - Methylprednisolone 1 gram daily for 3 days | No improvement in visual acuity |
| - Followed by prednisolone 1 mkd | ||||||
| - Oral methotrexate 15 mg weekly | ||||||
| - Oral warfarin | ||||||
| - Panretinal photocoagulation | ||||||
| Pelegrín et al. [12] (2012) | 42 | Male | Pakistani | Gradual loss of vision | - Prednisolone 60 mg/day | Stromal iris neovascularization was improved |
| - Aspirin 100 mg/day | ||||||
| - Oral methotrexate 20 mg/week | ||||||
| - Cataract surgery and pars plana vitrectomy | ||||||
| - Panretinal endophotocoagulation | ||||||
| - Intracameral and intravitreal injection of 1.25 μg/ 0.05 mL of bevacizumab | ||||||
| Demir et al. [13] (2010) | 14 | Female | Turkish | Gradual visual loss in both eyes | - Intravenous methylprednisolone 1 g/day for 3 days | Developed cataracts and eventually phthisis bulbi |
| - Followed by oral methotrexate 10 mg/day with oral steroids on a tapered basis | ||||||
| - Panretinal photocoagulation for four sessions | ||||||
| Koz et al. [14] (2007) | 45 | Male | Turkish | Fatigue, both upper extremity weakness, and blurring of vision | - Methylprednisolone 1 mkd | Died during bypass graft surgery |
| - Oral methotrexate 15 mg/week | ||||||
| - Cyclophosphamide therapy |
mkd, mg/kg of body weight per day.