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. 2020 Apr 3;37(8):2440–2449. doi: 10.1093/molbev/msaa087

Table 2.

Nomenclature for Overlapping Protein-Coding Reading Frames.

Studya Frameb
5′- 123123 -3′ 5′- 123 -3′ 5′- 123 - 3′ 5′- 123 -3′ 5′- 123 -3′ 5′- 123123 -3′
5′- 123123 -3′ 5′- 123123 -3′ 5′- 123123 -3′ 3′- 321321 -5′ 3′- 321321 -5′ 3′- 321321 -5′
OLGenie; Wei and Zhang (2015) Reference (ss11) ss12 ss13 sas11 sas12 sas13
Scherer et al. (2018) +1 +3 +2 −3 −2 −1
Lèbre and Gascuel (2017) +0 +2 +1 −1 −2 −0
Schlub et al. (2018) +0 +2 +1 −c2 −c1 −c0
Sabath et al. (2008) 0 2 (same-strand) 1 (same-strand) 1 (opposite-strand) 2 (opposite-strand) 0 (opposite-strand)
Belshaw et al. (2007) 0 −1 +1 rc-1 rc+1 rc0
Firth and Brown (2006) c 0 +2 +1 −1 −2 −3
Rogozin et al. (2002) c C1 C3 C2
Krakauer (2000) c +2 +1 −1 0 −2
Smith and Waterman (1980) c 0 2 1 5 3 4
a

Studies in descending order by year of publication.

b

Black denotes the reference frame and blue denotes the alternate frame; one alternate codon position is underlined to show overlap with reference codon position 1 (e.g., position 3 for ss13).

c

As reported by Lèbre and Gascuel (2017).