Table 2.
Associations between Baseline Levels of Kidney Function Indicators with Mortality under the Mixed-Effects Cox Model
| Variables |
Crude |
Adjusteda |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | pb | HR | 95% CI | pb | |
| BUN | ||||||
| Normal | ref | |||||
| Elevated | 11.07 | (9.49–12.91) | <0.001 | 6.27 | (5.29–7.42) | <0.001 |
| Scr | ||||||
| Normal | ref | |||||
| Elevated | 4.72 | (3.90–5.72) | <0.001 | 2.65 | (2.17–3.23) | <0.001 |
| BUA | ||||||
| Normal | ref | |||||
| Decreased | 2.92 | (2.45–3.48) | <0.001 | 2.10 | (1.75–2.51) | <0.001 |
BUA, blood uric acid; BUN, blood urea nitrogen; CI, confidence interval; HR, hazard ratio; Scr, serum creatinine. “Normal” indicates within the reference range; “elevated” indicates above the upper limit of normal; “decreased” indicates below the lower limit of normal.
a
In the mixed-effects Cox model, adjusted variables included age, gender, and comorbidities (hypertension, coronary heart disease, diabetes), and hospital site was treated as a random effect.
b
The p values were calculated based on the mixed-effects Cox model.