Table 6.
Genes expression in cerebellum of sham and mTBI mice.
| Gene | Treat | Time post mTBI | P value | ||||
|---|---|---|---|---|---|---|---|
| Week 10 | Week 19 | Week 28 | TBI effect | Time effect | Interaction | ||
| HK1 | Sham | 100.0 ± 8.4 | 107.8 ± 10.0 | 93.5 ± 9.6 | |||
| mTBI | 111.2 ± 10.3 | 86.2 ± 5.9 | 99.9 ± 9.5 | ||||
| PFK | Sham | 100.0 ± 4.1 | 107.4 ± 9.3 | 93.0 ± 5.0 | |||
| mTBI | 101.7 ± 5.6 | 93.7 ± 3.7 | 108.7 ± 8.3 | ||||
| PK | Sham | 100.0 ± 13.1 | 154.4 ± 15.8 | 259.0 ± 19.6 | <0.05 | <0.01 | |
| mTBI | 128.9 ± 12.7 | 180.7 ± 6.4 | 286.5 ± 12.9 | ||||
| PDH | Sham | 100.0 ± 22.1 | 120.0 ± 11.7 | 200.5 ± 21.1 | <0.01 | ||
| mTBI | 102.2 ± 13.6 | 146.5 ± 25.5 | 222.8 ± 23.6 | ||||
| Glut-1 | Sham | 100.0 ± 8.5 | 91.9 ± 5.7 | 79.1 ± 2.5 | <0.05 | ||
| mTBI | 94.4 ± 4.9 | 84.1 ± 4.0 | 83.7 ± 6.4 | ||||
| Glut-3 | Sham | 100.0 ± 5.4 | 111.9 ± 8.8 | 105.8 ± 5.2 | |||
| mTBI | 103.1 ± 5.9 | 91.4 ± 3.3 | 110.0 ± 7.2 | ||||
| MCT-1 | Sham | 100.0 ± 3.3 | 95.6 ± 4.3 | 93.2 ± 2.4 | |||
| mTBI | 103.7 ± 3.3 | 100.8 ± 2.7 | 97.9 ± 3.1 | ||||
| MCT-2 | Sham | 100.0 ± 9.6 | 116.1 ± 10.3 | 144.6 ± 3.5 | <0.01 | ||
| mTBI | 109.1 ± 10.1 | 96.9 ± 5.5 | 150.0 ± 8.9 | ||||
| HK2 | Sham | 100.0 ± 5.6 | 112.5 ± 6.0 | 82.4 ± 4.6 | <0.01 | ||
| mTBI | 103.8 ± 7.3 | 102.3 ± 5.2 | 82.8 ± 5.6 | ||||
| GPR 81 | Sham | 100.0 ± 9.5 | 117.0 ± 13.6 | 97.3 ± 12.5 | |||
| mTBI | 111.4 ± 17.1 | 103.6 ± 10.7 | 98.0 ± 8.2 | ||||
Data are presented as % change of expression level of the cerebellum in the sham group measured at week 10 post mTBI.
Data are mean ± SE (n = 9–10/group).
P Value: Obtained from Two-Way ANOVA analysis. If P > 0.05, the value is not listed on the table.