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. 2020 Oct 2;15(10):e0239130. doi: 10.1371/journal.pone.0239130

Table 2. Effect of SC and EX+SC on metabolic outcomes and adipokines.

SC EX+SC ANOVA (P-value) Effect Size
PRE POST PRE POST G T GxT Cohen’s d
Insulin Sensitivity 4.99±0.72 6.36±1.34 8.49±2.15 10.71±3.41 0.20 0.11 0.69 0.33
Glucose tAUC (mg/dL•120min) 13497±739 12687±424 15015±1277 14501±1160 0.22 0.15 0.74 0.18
(mg/dL•120min)in
FFA tAUC (mmol/L•120min) 39±7 41±7 40±7 44±6 0.81 0.61 0.82 0.13
(mEq/L•120min)
Insulin tAUC (μU/mL•120min) 3859±541 3736±961 2932±562 3093±717 0.38 0.97 0.79 0.14
(μU/ml•120min) ||
Adipokines (ng/mL)
    Leptin || 100.4±17.2 105.0±20.9 90.9±13.5 87.8±18.5 0.63 0.67 0.55 0.33
    HMW Adiponectin 1112.9±226.9 1179.6±229.5 2375.0±608.2 2240.0±520.8 0.98 0.05 0.98 0.59
    Total Adiponectin || 4877.1±629.3 4972.9±696.1 6216.4±1252.2 5360.6±1062.8 0.83 0.04 0.01 1.54
    HMW:Total 0.22±0.02 0.23±0.02 0.39±0.06 0.44±0.07 0.05 0.20 0.09 0.68
    HMW:Leptin 13.6±3.6 14.6±3.7 29.3±8.7 30.1±7.6 0.10 0.62 0.98 0.04

Data are means ± SEM. HMW adiponectin and the ratio of HMW to total adiponectin were covaried for baseline HMW adiponectin group differences (P = 0.09). ||Non-normally distributed data are presented in raw version for ease of interpretation. Conversions: Glucose, 1.00 mmol/L = 18.01 mg/dL; FFA, 1.00 mmol/L = 1.00 mEq/L; Insulin, 1.00 μU/mL = 6.95 pmol/L; Adipokines, 1.00 ng/mL = 0.001 μg/mL. Abbreviations: Total area under the curve (tAUC) for 120 min; free fatty acids (FFA); high molecular weight (HMW); group (G; SC vs. EX+SC); time (T; PRE vs. POST); group x time interaction (G x T).