. 2020 Oct 2;15(10):e0240154. doi: 10.1371/journal.pone.0240154

Table 2. Comparison of HIV co-receptors (CCR5 and α₄β₇) and memory marker (CD45RO) expression on T cells in mucosal cytobrush samples vs peripheral blood from HIV positive and negative women (n = 39; 22 HIV- & 17 HIV+).

parameter	parent population	cervical mucosa [median]	peripheral blood [median]	p-value
% CD4+	CD45+CD3+ T cells	41.9	50.3	0.178
% CD4+ (HIV-)	CD45+CD3+ T cells	54.1	60.3	0.147
% CD4+ (HIV+)	CD45+CD3+ T cells	23.9	24.2	0.384
CD4/CD8 ratio (HIV-)	CD45+CD3+ T cells	1.6	2	0.384
CD4/CD8 ratio (HIV+)	CD45+CD3+ T cells	0.4	0.4	0.525
CD4 MFI	CD45+CD3+ T cells	1788	3332	<0.001
% α₄β₇+	CD45+CD3+CD4+ T cells	20.6	17.8	0.646
% α₄β₇ MFI	CD45+CD3+CD4+ T cells	1204	1152	0.686
% CCR5+	CD45+CD3+CD4+ T cells	46.3	18.2	<0.001
CCR5+ MFI	CD45+CD3+CD4+ T cells	1957	2442	<0.001
% CD45RO+	CD45+CD3+CD4+ T cells	78.8	64.6	0.011
% α₄β₇+	CD45+CD3+CD4+CD45RO+T cells	20.4	19.1	0.618
% CCR5+	CD45+CD3+CD4+CD45RO+ T cells	49.1	23.9	<0.001
% CD8+	CD45+CD3+ T cells	44.8	38.6	0.666
CD8+ MFI	CD45+CD3+ T cells	5313	1994	<0.001
% α₄β₇+	CD45+CD3+CD8+ T cells	46.8	32.7	0.002
α₄β₇+ MFI	CD45+CD3+CD8+ T cells	1292	849	<0.001
% CCR5+	CD45+CD3+CD8+ T cells	65.6	28.8	<0.001
CCR5+ MFI	CD45+CD3+CD8+ T cells	2288	2283	0.7562
% CD45RO+	CD45+CD3+CD8+ T cells	43.6	25	<0.001

Table 2. Comparison of HIV co-receptors (CCR5 and α4β7) and memory marker (CD45RO) expression on T cells in mucosal cytobrush samples vs peripheral blood from HIV positive and negative women (n = 39; 22 HIV- & 17 HIV+).