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. 2020 Oct 2;15(10):e0230605. doi: 10.1371/journal.pone.0230605

Fig 1. Illustration of the Serial Block Face Scanning Electron Microscope (SBF SEM) images containing HeLa cells.

Fig 1

(a) Five representative 8192 × 8192 images arranged as 3D stack. The HeLa cells are the darker regions and the background is a brighter shade of grey. The red box indicates a region of interest (ROI)—a HeLa cell, that is magnified in (b). (b) Detail of the ROI with a single cell in the centre. This is slice 118 of 300. The nucleus is the large and fairly uniform region in the centre and it is surrounded by the nuclear envelope (NE) which is darker than the nucleus.