Table 3.
Correlations Cognitive Tests, Traditional Doppler Measures and Strain Indices.
Cognitive Test | n=Traditional Doppler and Cognition |
Surgical
Side Maximum PSV Kendall Tau Correlation |
Surgical Side MCA Mean Velocity Kendall Tau Correlation |
Surgical Side MCA PI Kendall Tau Correlation |
|||
r | p-value | r | p-value | r | p-value | ||
Verbal fluency (phonemic)* | 40 | −0.09 | 0.433 | −0.12 | 0.303 | 0.08 | 0.475 |
Psychomotor speed | 40 | −0.09 | 0.444 | 0.03 | 0.814 | −0.08 | 0.509 |
Speeded mental flexibility* | 39 | −0.05 | 0.654 | 0.09 | 0.403 | −0.02 | 0.875 |
Verbal learning* | 40 | −0.10 | 0.369 | 0.05 | 0.683 | 0.12 | 0.293 |
Delayed verbal memory* | 40 | −0.11 | 0.315 | 0.20 | 0.072 | 0.02 | 0.842 |
Visuospatial construction* | 39 | −0.13 | 0.276 | −0.01 | 0.922 | −0.12 | 0.298 |
Auditory attention/working memory* | 40 | −0.14 | 0.239 | −0.20 | 0.083 | 0.03 | 0.786 |
Delayed visual memory* | 39 | −0.02 | 0.828 | 0.09 | 0.417 | −0.10 | 0.396 |
Maximum Axial Stain | Maximum Lateral Strain | Maximum Shear Strain | |||||
Cognitive Test | n=Strain and Cognition | Kendall Tau Correlation | Kendall Tau Correlation | Kendall Tau Correlation | |||
r | p-value | r | p-value | r | p-value | ||
Verbal fluency (phonemic)* | 40 | −0.20 | 0.081 | −0.22 | 0.046 | −0.14 | 0.202 |
Psychomotor speed | 40 | −0.40 | <0.001 | −0.25 | 0.031 | −0.35 | 0.003 |
Speeded mental flexibility* | 39 | −0.35 | 0.002 | −0.29 | 0.010 | −0.35 | 0.002 |
Verbal learning* | 40 | −0.18 | 0.115 | −0.08 | 0.476 | −0.05 | 0.649 |
Delayed verbal memory* | 40 | −0.16 | 0.161 | −0.01 | 0.963 | −0.03 | 0.779 |
Visuospatial construction* | 39 | −0.13 | 0.276 | −0.04 | 0.760 | −0.10 | 0.385 |
Auditory attention/working memory* | 40 | −0.24 | 0.036 | −0.10 | 0.396 | −0.01 | 0.906 |
Delayed visual memory* | 39 | −0.20 | 0.077 | −0.12 | 0.276 | −0.22 | 0.050 |
Verbal fluency (phonemic): Controlled Oral Word Association Test; psychomotor speed: Digit Symbol subtest from the WAIS-IV; speeded mental flexibility: Trail Making Test B; verbal learning: Hopkins Verbal Learning Test–Revised Total Learning; delayed verbal memory: Hopkins Verbal Learning Test–Revised Delayed Recall; visuospatial construction: Block Design Subtest from the WAIS IV; auditory attention/working memory: Digit Span subtest from the WAIS-IV; delayed visual memory: Rey Complex Figure Delayed Recall. Modified with permission from Mitchell C, Wilbrand SM, Cook TD, Meshram NH, Steffel CN, Nye R, Varghese T, Hermann BP and Dempsey RJ. Traditional Doppler Measures Do Not predict Cognition in a Cohort With Advanced Atherosclerosis. Stroke. 50:Suppl_1 abstract WMP47.49
MCA=middle cerebral artery, PI=pulsatility index, PSV=peak systolic velocity.