Table 1.
Study characteristics: cancer therapy duration, demographic and clinical characteristics, sample size, supervised and nonsupervised exercise prescription, and outcomes assessed.
Author (year) | Cancer therapy duration | Demographical and clinical characteristics | Face-to-face supervised exercise period | Unsupervised home-based exercise period | Outcomes |
---|---|---|---|---|---|
Galvão et al (2014) [3] | Previous AST duration of ∼12 mo with time since its cessation of 38 mo | Age: 71.4 yr; II–IV; Previous AST and radiotherapy |
Combined resistance and aerobic training: n = 50, 2 sessions per week for 24 wk; RT: 2–4 sets of 6–12 RM; AT: 20–30 min at 70–85% HR |
24 wk; booklet with detailed information about a home exercise prescription including resistance, aerobic, and flexibility exercises | Fat mass, lean mass, SF-36 a |
Taaffe et al (2017) [4]b | Minimum exposure to AST of 2 mo and anticipated to receive AST for the subsequent 12 mo | Age: 68.8 yr; Localised and nodal metastases; Gleason score: 7.8; AST AST plus radiotherapy AST plus antiandrogen AST plus surgery |
Combined resistance and aerobic training: n = 54, 2 sessions per week for 24 wk; AT: 20–30 min at 60–85% HR; RT: 2–4 sets of 6–12 RM |
24 wk; home-based programme that recommended 150 min of aerobic exercise per week and resistance exercise using body weight and resistance bands | EORTC QLQ-C30Fatiguec |
Ndjavera et al (2020) [5] | Patients with newly diagnosed prostate cancer and beginning AST treatment | Age: 72.0 yr; Locally advanced and metastatic patients; Gleason score range from 6 to 10; ASTAST plus radiotherapy |
Combined resistance and aerobic training: n = 24, 2 sessions per week for 12 wk; AT: 6 bouts of 5 min at 55–85% HR; RT: 2–4 sets of 10 reps at 11–15 RPE |
12 wk; patients were instructed to continue exercising and maintain self-directed levels of physical activity | Fat mass, FACT-P a, FACIT-Fatigue c |
Newton et al (2019) [6]b | Minimum exposure to AST of 2 mo and anticipated to receive AST for the subsequent 12 mo | Age: 69.0 yr; Localised and nodal metastases; Gleason score: 7.8; AST AST plus radiotherapy AST plus antiandrogen |
Combined resistance and aerobic training:n = 50, 2 sessions per week for 24 wk; AT: 20–30 min at 60–85% HR; RT: 2–4 sets of 6–12 RM | 24 wk; home-based programme that recommended 150 min of aerobic exercise per week and resistance exercise using body weight and resistance bands | Fat mass, lean mass |
AST = androgen suppression therapy; AT = aerobic training; EORTC QLQ-C30 = European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30; FACIT = Functional Assessment of Chronic Illness Therapy; FACT-P = Functional Assessment of Cancer Therapy—Prostate; HR = hear rate; RM = repetitions maximum; RPE = rate of perceived exertion; RT = resistance training; SF-36 = 36-Item Short Form Survey.
Included in quality-of-life meta-analysis.
Papers derived from the same trial.
Included in fatigue meta-analysis.