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letter
. 2020 Oct 2;21:47–50. doi: 10.1016/j.euros.2020.09.002

Table 1.

Study characteristics: cancer therapy duration, demographic and clinical characteristics, sample size, supervised and nonsupervised exercise prescription, and outcomes assessed.

Author (year) Cancer therapy duration Demographical and clinical characteristics Face-to-face supervised exercise period Unsupervised home-based exercise period Outcomes
Galvão et al (2014) [3] Previous AST duration of ∼12 mo with time since its cessation of 38 mo Age: 71.4 yr;
II–IV;
Previous AST and radiotherapy
Combined resistance and aerobic training:
n = 50, 2 sessions per week for 24 wk; RT: 2–4 sets of 6–12
RM; AT: 20–30 min at 70–85% HR
24 wk; booklet with detailed information about a home exercise prescription including resistance, aerobic, and flexibility exercises Fat mass, lean mass, SF-36 a
Taaffe et al (2017) [4]b Minimum exposure to AST of 2 mo and anticipated to receive AST for the subsequent 12 mo Age: 68.8 yr;
Localised and nodal metastases;
Gleason score: 7.8;
AST AST plus radiotherapy AST plus antiandrogen AST plus surgery
Combined resistance and aerobic training:
n = 54, 2 sessions per week for 24 wk; AT: 20–30 min at
60–85% HR; RT: 2–4 sets of 6–12 RM
24 wk; home-based programme that recommended 150 min of aerobic exercise per week and resistance exercise using body weight and resistance bands EORTC QLQ-C30Fatiguec
Ndjavera et al (2020) [5] Patients with newly diagnosed prostate cancer and beginning AST treatment Age: 72.0 yr;
Locally advanced and metastatic patients;
Gleason score range from 6 to 10;
ASTAST plus radiotherapy
Combined resistance and aerobic training:
n = 24, 2 sessions per week for 12 wk; AT: 6 bouts of 5 min
at 55–85% HR; RT: 2–4 sets of 10 reps at 11–15 RPE
12 wk; patients were instructed to continue exercising and maintain self-directed levels of physical activity Fat mass, FACT-P a, FACIT-Fatigue c
Newton et al (2019) [6]b Minimum exposure to AST of 2 mo and anticipated to receive AST for the subsequent 12 mo Age: 69.0 yr;
Localised and nodal metastases;
Gleason score: 7.8;
AST AST plus radiotherapy AST plus antiandrogen
Combined resistance and aerobic training:n = 50, 2 sessions per week for 24 wk; AT: 20–30 min at 60–85% HR; RT: 2–4 sets of 6–12 RM 24 wk; home-based programme that recommended 150 min of aerobic exercise per week and resistance exercise using body weight and resistance bands Fat mass, lean mass

AST = androgen suppression therapy; AT = aerobic training; EORTC QLQ-C30 = European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30; FACIT = Functional Assessment of Chronic Illness Therapy; FACT-P = Functional Assessment of Cancer Therapy—Prostate; HR = hear rate; RM = repetitions maximum; RPE = rate of perceived exertion; RT = resistance training; SF-36 = 36-Item Short Form Survey.

a

Included in quality-of-life meta-analysis.

b

Papers derived from the same trial.

c

Included in fatigue meta-analysis.