Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 26;9:e59810. doi: 10.7554/eLife.59810

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020, Geisberg et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Figure 7. — The 3’UTRs of speed-sensitive genes contain purine-rich elements (red line segments) and pyrimidine-rich elements (blue line segments) of varying strengths (small, medium or large scissors). Under normal conditions (exponentially-growing wild-type cells), cleavage and polyadenylation takes place predominantly at pyrimidine-rich elements. In diauxic conditions and in cells harboring slow Pol II, purine-rich elements drive an upstream shift in polyadenylation patterns, likely due to increased Pol II dwell time at those sequences. Conversely, fast Pol II shifts the poly(A) patterns to more distal purine rich sites.