Table 3.
The Association Between the CVD History and VCAM-1 in 163 Patients with COPD by Logistic Regression Analysis
| Variables | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
| VCAM-1 levels (ng/mL) | |||
| Quartile 1 | 1.000 (ref.) | 1.000 (ref.) | 1.000 (ref.) |
| Quartile 2 | 1.314 (1.120–1.689) | 1.245 (1.116–1.608) | 1.215 (1.112–1.493) |
| Quartile 3 | 1.476 (1.235–1.924) | 1.415 (1.220–1.855) | 1.345 (1.183–1.751) |
| Quartile 4 | 1.964 (1.463–3.459) | 1.841 (1.396–2.995) | 1.750 (1.324–2.428) |
| P-trend | <0.001 | 0.001 | 0.012 |
Notes: Model 1: Adjusted for age and gender, Model 2: Adjusted for age, gender, BMI, current smoker, current drinker, admission systolic and diastolic BP, LVEF and treatments, Model 3: Adjusted for age, gender, BMI, current smoker, current drinker, admission systolic and diastolic BP, LVEF, treatments and laboratory measurements.
Abbreviations: CVD, cardiovascular disease; COPD, chronic obstructive pulmonary disease; VCAM-1, vascular cell adhesion molecule-1; BMI, body mass index; BP, blood pressure; LVEF, left ventricular ejection fraction.