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. 2020 Sep 28;13:9587–9597. doi: 10.2147/OTT.S251830

Figure 1.

Figure 1

TP53INP2 expression in bladder cancer tissues and cells.

Notes: (A) The relative expression quantities of TP53INP2 in 16 pairs of bladder cancer tissues and paired adjacent nontumor tissues were detected using qRT-PCR. (B) IHC staining of TP53INP2 in 16 BC tissues and paired 16 adjacent non-tumor tissues obtained from patients with bladder cancer. Scale bar, 50 μm. (C) The TP53INP2 expression levels were detected in the human normal urothelial cell line SV-HUC-1 and in five types of human bladder cancer cell lines, including 5637, EJ, BIU87, UM-UC-3, and T24, via qRT-PCR. (D) Overall survival of the 402 bladder cancer patients was analyzed in accordance with the TP53INP2 expression level in the TCGA database by GEPIA. **** p < 0.001; * p < 0.05.

Abbreviations: qRT-PCR, real-time quantitative PCR; IHC, immunohistochemistry; BC, bladder cancer; TCGA, the cancer genome atlas; GEPIA, gene expression profiling interactive analysis; ns, no statistical significance.