Table 2.
Demographic and clinical variables of the study participants.
| HC (n = 12) | AD (n = 31) | p Value | |
|---|---|---|---|
| Age (years (median, IQR)) | 69 (60, 70) | 69 (67, 74) | 0.072 |
| Gender (female, n (%)) | 4 (33%) | 18 (58%) | 0.146 |
| CSF β-Amyloid (pg mL-1) (median (IQR)) | 1178 (1031, 1414) | 552 (465, 678) | < 0.001* |
| CSF total Tau (pg mL-1) (median (IQR)) | 274 (167, 368) | 641 (387, 1043) | 0.002* |
| CSF phosphorylated Tau (pg mL-1) (median (IQR)) | 44 (36, 57) | 101 (71, 146) | < 0.001* |
| CDR (median, IQR) | 0 (0, 0) | 0.5 (0.5, 1) | < 0.001* |
| MMSE (median, IQR) | 30 (28, 30) | 24 (18, 26) | < 0.001* |
| RBANS.MI (median, IQR) | 86 (81, 95) | 53 (40, 73) | < 0.001* |
| RBANS.VC (median, IQR) | 201 (81, 116) | 72 (56, 89) | 0.001* |
| RBANS.L (median, IQR) | 92 (83, 95) | 60 (51, 82) | < 0.001* |
| RBANS.A (median, IQR) | 97 (84, 100) | 60 (56, 79) | < 0.001* |
| RBANS.DM (median, IQR) | 98 (89, 105) | 48 (40, 60) | < 0.001* |
| FAQ (median, IQR) | 0 (0, 1) | 6 (1, 13) | < 0.001* |
*p < 0.05.
IQR: Interquartile range, CDR, clinical dementia rating, RBANS: repeatable battery for the assessment of neuropsychological status (immediate memory [RBANS.IM], visuospatial/constructional [RBANS.V/C], language [RBANS.L], attention [RBANS.A], delayed memory [RBANS.DM]). FAQ: Functional Activities Questionnaire.