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. 2020 Sep 28;14:3983–3993. doi: 10.2147/DDDT.S264077

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© 2020 Yao et al.

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The effect of compound 7594–0037 on MM cell apoptosis. (A–B) RPMI-8226 cells treated with different doses of compound 7594–0037 were stained with Annexin V-FITC/PI, and flow cytometry analysis showed the ratio of apoptotic cells. (C) Percentages of U266 cell apoptosis based on three independent experiments of flow cytometry assay. (D) Western blot detection of apoptosis-associated PARP1, caspase-9, and caspase-3 proteins in RPMI-8226 and U266 cells treated with compound 7594–0037. Error bars: mean ± SD; *P<0.05.