Figure 10.
Effect of WFA on the CCl4-induced liver fibrosis in WT and SIRT3 KO mice. (a–c) The serum levels of HA, LN, and PC-III were examined in both WT and SIRT3 KO mice. (d–f) Real-time PCR analyses of α-SMA, fibronectin, and α1(I) procollagen in liver tissues. GAPDH was used as the invariant control. (g) Western blot analyses of liver proteins with densitometry. Representative blots were from three independent experiments. (h–j) Quantified western blot results of liver proteins. For the statistics of each panel in this figure, data are expressed as mean ± SD (n = 3). ∗p < 0.05 and ∗∗p < 0.01.