Table 6.

Subgroup analysis of studies on periodontitis and prostate cancer

Subgroup	No. of studies	Heterogeneity		Model	Meta-analysis
		I2 (95%CI)	p		HR	95%CI	p
Overall analysis	4	0% (0%-85%)	0.60	Random	1.20	1.09-1.31	0.0002
Periodontitis severity
Mild/moderate	2	0%	0.41	Random	1.14	0.95-1.37	0.17
Severe	2	0%	0.48	Random	1.34	1.06-1.68	0.01
Adjusted covariates
With smoking status	4	0% (0%-85%)	0.60	Random	1.20	1.09-1.31	0.002
With socio-economic status	3	0% (0%-58%)	0.40	Random	1.20	1.08-1.33	0.0007
Mean age
≤60	2	11% (0%-43%)	0.29	Random	1.26	1.03-1.54	0.02
>60	2	0%	0.53	Random	1.18	1.05-1.31	0.001
Sample size
≤15000	2	0%	0.42	Random	1.30	1.09-1.55	0.004
>15000	2	0%	0.87	Random	1.16	1.03-1.29	0.01

No. of studies: the number of studies.