Table 2.
Hazard ratios (HRs) and 95% confidence intervals (CIs) for risk of cancer in different eGFR groups
| eGFR (ml/min/1.73m2) | N (%) | No. of case | Incidence rate | HR (95% CI) a | P | HR (95% CI) b | P | HR (95% CI) c | P | HR (95% CI) d | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ≥ 90 | 7235 (62.9%) | 117 | 431 | 1 [reference] | - | 1 [reference] | - | 1 [reference] | - | 1 [reference] | - |
| 60 to 89 | 3880 (33.7%) | 79 | 550 | 1.28 (0.96, 1.70) | 0.09 | 1.05 (0.76, 1.44) | 0.78 | 1.01 (0.73, 1.39) | 0.96 | 1.01 (0.73, 1.39) | 0.96 |
| < 60 | 393 (3.4%) | 21 | 1515 | 3.57 (2.24, 5.68) | <0.001 | 2.48 (1.47, 4.18) | 0.001 | 2.24 (1.32, 3.80) | 0.003 | 2.08 (1.22, 3.53) | 0.007 |
| Per 10 units decrease | 11 508 | 217 | 506 | 1.20 (1.11, 1.30) | <0.001 | 1.12 (1.02, 1.23) | 0.02 | 1.10 (1.00, 1.21) | 0.06 | 1.09 (0.99,1.20) | 0.09 |
Note: Incidence rates were expressed as per 100 000 person-years.
a Unadjusted; b Adjusted for age, sex and smoking; c Adjusted for age, sex, smoking, education, PCE, BMI, drinking, diabetes, hypertension, dyslipidemia;d Adjusted for all above and micro-inflammation.