Table 3.
Sensitivity analysis of the association between different eGFR groups and risk of cancer
| eGFR (ml/min/1.73m2) | N | No. of cases | HR (95% CI)a | P | HR (95% CI)b | P | HR (95% CI)c | P | HR (95% CI)d | P |
|---|---|---|---|---|---|---|---|---|---|---|
| ≥ 90 | 7179 | 61 | 1 [reference] | - | 1 [reference] | - | 1 [reference] | - | 1 [reference] | |
| 60 to 89 | 3846 | 45 | 1.41 (0.96, 2.07) | 0.08 | 1.03 (0.66, 1.57) | 0.90 | 1.00 (0.65, 1.54) | 0.92 | 1.00 (0.65, 1.54) | 0.93 |
| < 60 | 386 | 14 | 4.68 (2.61, 8.37) | <0.001 | 2.61 (1.34, 5.09) | 0.01 | 2.41 (1.22, 4.75) | 0.01 | 2.27 (1.15, 4.47) | 0.02 |
| Per 10 units decrease | 11 411 | 120 | 1.24 (1.12, 1.38) | <0.001 | 1.10 (0.97, 1.26) | 0.15 | 1.09 (0.95, 1.24) | 0.21 | 1.07 (0.94, 1.23) | 0.30 |
Note: a Unadjusted; b Adjusted for age, sex and smoking; c Adjusted for age, sex, smoking, education, PCE, BMI, drinking, diabetes, hypertension, dyslipidemia;d Adjusted for all above and micro-inflammation.