Table 1.
Synthesis analysis of the association between rs895819 and cervical cancer risk
| Quantitative synthesis | n a | Heterogenous | Homogenous | Dominant | Recessive | Additive | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) b | P c | OR (95% CI) b | P c | OR (95% CI) b | P c | OR (95% CI) b | P c | OR (95% CI)b | P c | ||
| Analysis 1d | 2 | 0.79 (0.44-1.42) | 0.039 | 1.13 (0.18-7.26) | <0.001 | 0.86 (0.38-1.93) | 0.002 | 0.47 (0.27-0.82) | 0.294 | 0.94 (0.40-2.19) | <0.001 |
| Analysis 2e | 2 | 0.71 (0.20-2.52) | 0.015 | 0.88 (0.14-5.65) | <0.001 | 0.83 (0.16-4.32) | 0.001 | 1.17 (0.52-2.63) | 0.002 | 1.06 (0.46-2.48) | <0.001 |
a Number of comparisons.
b The crude OR and 95% CI were calculated based on the genotype frequencies.
c P value of Q-test for heterogeneity analysis.
d The genetic variant comparisons in Analysis 1 were TC versus TT, CC versus TT, TC/CC versus TT, CC versus TT/TC and C versus T for heterogenous, homogenous, dominant, recessive and additive model respectively.
e The genetic variant comparisons in Analysis 2 were TC versus CC, TT versus CC, TC/TT versus CC, TT versus CC/TC and T versus C for heterogenous, homogenous, dominant, recessive and additive model respectively.