Table 3.

Univariate and multivariate analyses of clinical parameters and overall prognosis for HCC patients

Multivariate analysis of clinical parameters
	HR (hazard ratio)	95% CI	P
Age	0.511	0.337-0.777	0.002
≤55 year vs >55 year
IL36	0.432	0.271-0.688	0
Positive vs Negative
AFP	1.722	1.149-2.679	0.008
≤400 ng/ml vs >400 ng/ml
Univariate analysis of clinical parameters
	HR (hazard ratio)	95%CI	P
Gender	0.691	0.483-0.988	0.043
Male vs Female
Age (years)	0.661	0.458-0.954	0.027
≤55 vs >55
Tumor size (cm)	1.026	0.717-0.501	0.069
≤4.5 vs >4.5
Liver cirrhosis	1.541	1.076-2.207	0.018
Yes vs No
TNM stage	0.717	0.501-1.026	0.069
I-II vs III-IV
Metastasis	1.331	0.928-1.909	0.121
Yes vs No
HBV	1.194	0.837-1.703	0.329
Yes vs No
HCV	1.304	0.896-1.898	0.165
Yes vs No
Child-pugh class	0.693	0.484-0.993	0.046
A class vs B class
Edmondson class	0.814	0.568-1.167	0.263
III vs IV
Surgery	0.538	0.374-0.774	0.001
Radical resection vs palliative resection
Post-operative TACE	1.222	0.856-1.743	0.27
Yes vs No
IL36	0.393	0.247-0.626	0
Positive vs Negative