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Comparison of hepatocellular carcinoma tumor formation in rats after drug treatment
| Oncogenesis | placebo (n=20) | celecoxib (n=19) | metformin (n=14) | combination (n=17) |
|---|---|---|---|---|
| No | 7 (35) | 12 (63.2) | 8 (57.1) | 14 (82.4)a |
| Yes | 13 (65) | 7 (36.8) | 6 (42.9) | 3 (17.6) |
Values are shown as n (%);
a P<0.05 compared to the placebo group.
