Fig. 8. RIC enhanced survival during and after NEC and this effect was abolished following administration of H2S-synthesizing enzyme inhibitors.
a After P9, pups from all groups except breastfed (BF) controls, continued to receive gavage feeding three times per day by single investigator blinded to treatment allocation and were monitored until death occurred. Pups receiving Stage 1 or 2 RIC survived significantly longer after NEC induction (*p < 0.05; **p < 0.01). b Survival rate after P9 was similar between NEC pups and NEC pups receiving Stage 1 or 2 RIC and given H2S-synthesizing enzyme inhibitors (*p < 0.05; **p < 0.01). Survival curves were compared using the logrank test (*p < 0.05; **p < 0.01). Data are presented as mean ± SEM. Source data are provided as a Source Data file.