Table 2.

Multivariate Cox regression analysis in the OS patients

Variables	Multivariate analysis
	HR	95% CI	P value
miR-455-3p	2.951	1.124–7.747	0.028
Age	1.837	0.771–4.378	0.170
Gender	1.604	0.683–3.765	0.278
Tumor size	2.194	0.753–6.393	0.150
Differentiation	2.201	0.863–5.202	0.101
Distant metastasis	2.119	0.863–5.202	0.101
Tumor site	2.775	0.662–11.635	0.163
Clinical stage	4.095	1.136–14.767	0.031

OS osteosarcoma