Fig. 4.

Escapee genes. a Browser plot showing tight association of replication timing and PMD state. b Replication timing for 50-kb bins inside PMDs with high ($>66\%$) medium (33-66%) or low (0–33%) mean methylation level. c Stitched browser plot showing 6 most conserved escapee genes in human and their methylation state in other species. d Escapee replication timing violin plots. e TPM distributions for genes inside PMDs, escapees, and outside of PMDs in PMD-containing samples and healthy analogues