Figure 7.

Transfer of FTM promoted leptin-induced browning remodeling in white adipocytes. (A-C) Energy expenditure and average AUC analysis of oxygen consumption (VO₂), carbon dioxide (VCO₂) and heat (expressed as Kcal/h) during a 12-h light/dark cycle in HFD+FTM and HFD mice. (D) Body weight and body composition of HFD mice treated with vehicle or FTM (n = 6). (E-F) Serum ALT and AST of HFD mice treated with vehicle or FTM. (G) Relative protein expression of PRDM-16, leptin and phosphorylated STAT3 in HFD-fed mice treated with vehicle or FTM. (H) Representative fluorescence images showing the expression of UCP-1 (red) and PRDM-16 protein (green) in E-WAT and S-WAT of HFD mice treated with vehicle or FTM.