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. 2020 Sep 2;10(24):11063–11079. doi: 10.7150/thno.45674

Figure 5.

Figure 5

CSRP2 affectes the Hippo, ERK, and PAK signaling pathways and the pseudopodia formation in CRC cells. (A) WB was performed to detect the activation of Hippo and ERK pathways in CSRP2-overexpressed or -depleted CRC cells and control cells. (B) WB was performed to detect the activation of PAK, LIMK and cortactin in CSRP2-overexpressed or -depleted CRC cells and control cells. (C) IF staining analyzes the pseudopodia of CSRP2-overexpression CRC cells. (D) Phalloidin IF staining analyzes the pseudopodia of CSRP2-depletion CRC cells. (E) The pseudopodia of CSRP2-overexpression CRC cells was detected by scanning electron microscope; (F) The pseudopodia of CSRP2 depletion cells was detected by SEM.