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. 2020 Sep 14;10(24):11264–11277. doi: 10.7150/thno.47039

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Consensus Cluster of the expression of 188 functional eRNAs reveals three distinct integrated clusters in lung adenocarcinoma patients. A. Heatmap representation of 188 functional eRNAs in three clusters. B. Number of mutations and fraction of copy number alter genomes per sample in three clusters. C. Gene Set Enrichment Analysis (GSEA) of genes differentially expressed in lung adenocarcinoma patients in Cluster 3 from patients in the other two clusters. The x-axis and the size of circles indicate the normalized enrichment score (NES) of each pathway. D. Survival analysis reveals a prognostic prediction effect of eRNA-based clusters.