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NOX2 deficiency abolishes the toxic effects caused by FL in mice. (A) Experimental protocol. (B) NOX2 protein expression (n = 6). (C) Body weight gain (n = 10). (D) EF in the indicated groups (n = 8). (E) CK-MB levels (n = 6). (F) DHE staining and statistical results (n = 6). (G) MDA level after NOX2 deficiency (n = 6). *P < 0.05 versus matched control.
