Table 3.
Diagnostic performance and parameters of the nine serological indicators.
| Index | NLR | PLR | LMR | HsCAR | dNLR | PNI | SII | AFR | HsCPAR |
|---|---|---|---|---|---|---|---|---|---|
| AUC | 0.75 | 0.68 | 0.62 | 0.81 | 0.76 | 0.76 | 0.72 | 0.72 | 0.80 |
| Best Cut-off Value | 5.08 | 229.09 | 2.56 | 0.71 | 3.39 | 340.05 | 809.02 | 6.51 | 0.58 |
| Sensitivity (%) | 63.79 | 63.79 | 56.90 | 82.76 | 63.79 | 86.21 | 72.41 | 68.97 | 58.62 |
| Specificity (%) | 82.14 | 71.43 | 66.07 | 80.36 | 85.71 | 60.71 | 67.86 | 73.21 | 92.86 |
| Negative Predictive Value (%) | 68.66 | 65.57 | 59.68 | 81.82 | 69.57 | 80.95 | 70.37 | 69.49 | 68.42 |
| Positive Predictive Value (%) | 78.72 | 69.81 | 63.46 | 81.36 | 82.22 | 69.44 | 70.00 | 72.73 | 89.47 |
| True Positive Rate (%) | 63.79 | 63.79 | 56.90 | 82.76 | 63.79 | 86.21 | 72.41 | 68.97 | 58.62 |
| False Positive Rate (%) | 17.86 | 28.57 | 33.93 | 19.64 | 14.29 | 39.29 | 32.14 | 26.79 | 7.14 |
| True Negative Rate (%) | 82.14 | 71.43 | 66.07 | 80.36 | 85.71 | 60.71 | 67.86 | 73.21 | 92.86 |
| False Negative Rate (%) | 36.21 | 36.21 | 43.10 | 17.24 | 36.21 | 13.79 | 27.59 | 31.03 | 41.38 |
| Accuracy (%) | 72.81 | 67.54 | 61.40 | 81.58 | 74.56 | 73.68 | 70.18 | 71.05 | 75.44 |
| Precision (%) | 78.72 | 69.81 | 63.46 | 81.36 | 82.22 | 69.44 | 70.00 | 72.73 | 89.47 |
| Youden Index | 145.94 | 135.22 | 122.97 | 163.12 | 149.51 | 146.92 | 140.27 | 142.18 | 151.48 |
Abbreviations: AUC, area under ROC curve; NLR, neutrophil–lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; dNLR, derived neutrophil–lymphocyte ratio; HsCAR, high sensitivity C-reactive protein-albumin ratio; AFR, albumin-to-fibrinogen ratio; PNI, prognostic nutritional index; SII, systemic immune-inflammation index; HsCPAR, high sensitivity C-reactive protein-prealbumin ratio.