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. 2020 Sep 2;12(9):e10208. doi: 10.7759/cureus.10208

Table 2. Key studies selected in our review.

GBS: Guillain Barré syndrome

Author name Publication Month-Year Type of Study Focus of study Result / Conclusion
Sanz et al [5] August 2019 Systematic literature review Assess the risk of GBS after Pandemic & Seasonal influenza vaccine GBS should be considered less common adverse event following influenza vaccine but it should affect vaccine acceptance.
Petras et al [8] March 2020 Meta-analysis Risk of GBS following seasonal influenza vaccine The meta-analysis did not find association between GBS & seasonal influenza vaccine
Gattas et al [9] December 2018 Retrospective observational GBS & Seasonal trivalent influenza vaccine association Post vaccination GBS is rare but should be monitored closely by health authorities
Bardenheier et al [11] August 2018 Retrospective observational Compare adverse event following pandemic and seasonal influenza vaccine in military vs civilian population aged 17-44 years Incidence of GBS is four times higher in military population than civilian population.
Park et al [15] July 2017 Retrospective Observational Clinical and Laboratory features of GBS after influenza immunization GBS should be suspected six weeks following immunization in the absence of clear alternative diagnosis to improve diagnostic accuracy and Brighton criteria is used for evaluation of post-vaccine GBS.
Dieleman et al [18] July 2011 Case-control Assess the risk of GBS after H1N1 pandemic influenza vaccine No risk of GBS after the pandemic influenza vaccine when adjusted with influenza like illness and seasonal influenza vaccine.
Kuo et al [21] July 2019 Case control Association between GBS & Trivalent influenza vaccine in patient aged >50 years Trivalent influenza vaccine has no association with GBS after 50 years of age
Prestel et al [27] November 2014 Case series Risk of GBS & variant Fisher syndrome following H1N1 pandemic influenza vaccine High risk of GBS & Variant Fisher syndrome in temporal association with pandemic influenza vaccine