Figure 8.

H&E staining and Masson’s trichrome staining evaluation of the effects of MgN, NT and blank-Ti on bone regeneration.

Notes: Four weeks after implantation, cubic and short pre-osteoblasts were lined surrounding the trabecular bone and MgN implants. On the same day, newly generated small vessels were scattered in trabecular bone. Angiogenesis and osteogenesis were intricately modulated in the formation of bone tissues. The MgN group showed robust new formation of bone tissues, which delimited the defected area with the implantation of MgN implant. The defected area filled by the blank Ti and NT groups showed less bone area than that of MgN group, indicating that MgN could enhance the formation of bone tissues compared with the NT and blank-Ti groups.

Abbreviation: H&E staining, hematoxylin and eosin staining.