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. 2020 Apr 10;77(20):3963–3976. doi: 10.1007/s00018-020-03515-w

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© The Author(s) 2020

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Fig. 1 — Different stages of a single interaction unit. “NLR” monitors effector target “I”, important for immunity, and activates lesions when “I” is affected by mutations or ETI when “I” is influenced by the 1st ETS effector “A”. Effector “B” prevents activation of NLR, whereby “B” confers 2nd ETS