Table 1.

Distinct functions of the phosphorylation sites in CREB

Serine residue	Molecular association	Induction of activity	Inhibition of activity	Cell growth	Cell mobility	Inhibition of apoptosis	Cell differentiation	Induction of transcription	Inhibition of transcription
Ser108	X
Ser111	X								X
Ser114	X
Ser117
Ser121			X						X
Ser129				X				X
Ser133		X		X	X	X	X	X