Table 3. L, [A+B], and D mtDNA haplogroup cybrids each displayed unique overall results in cell and gene expression studies.
Results from the cell and gene expression studies were congregated into one table. As illustrated, each haplogroup had a unique result when observed in large as a summation of the assays and gene expression results. As demonstrated from the cell and gene expression studies, L cybrids had decreased cellular metabolic activity and ALK gene expression after cisplatin treatment (p = 0.0117, p < 0.0001 respectively). [A+B] cybrids had decreased cellular metabolic activity, ALK gene expression, and EGFR gene expression after cisplatin treatment (p = 0.0285, p = 0.0001, p = 0.0246, respectively). D cybrids had decreased cellular metabolic activity after cisplatin treatment (p = 0.0001). ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
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