Table 2. Optimal programming of closed loop stimulation (CLS) for vasovagal syncope patients. Adapted from Kanjwal K, Grubb BP. Journal of Innovations in Cardiac Rhythm Management 2011;2:395-9. 33.

1	Resting Rate Control should be turned “off” to allow CLS algorithm to vary rate response from base rate to the maximum programmed CLS rate based on cardiac impedance measurement variations, enabling earlier intervention
2	Set pacing mode to “DDD-CLS”, with lower rate of 60-65 beats/min, upper tracking rate of 160 beats/min, and maximum CLS rate (maximum sensor rate) between 130-140 beats/min
3	CLS response (aggressiveness of the CLS algorithm) should be set to “high” or “very high”.