Table 2. Cumulative fraction of response (%) of tigecycline with various dosing regimens met each pharmacokinetic/pharmacodynamic targets.

Loading dose (mg)	Maintenance dose (mg)	Cumulative fraction of response (%)
		fAUIC24 >6.9	fAUIC24 >17.9
100	50 mg q 12 hr	99.9	93
200	100 mg q 24 hr	99.9	93
150	75 mg q 12 hr	100	96.2
150	150 mg q 24 hr	100	96.2
200	100 mg q 12 hr	100	98.9
200	200 mg q 24 hr	100	99

fAUIC₂₄, ratio of the free area under the curve to minimum inhibitory concentration.