Table 1. Studies of convalescent plasma therapy for treating COVID-19.
Authors, Year of publication | Country | Study design | Number of participants | Clinical outcomes | Adverse events | Reference | ||
---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | |||||
Abolghasemi et al., 2020 | Iran | Nonrandomized, controlled study | 115 | 74 | 14.8% died | 24.3% died | Not reported | [27] |
Ahn et al., 2020 | Korea | Nonrandomized, non-controlled study | 2 | 100% improved | None | [23] | ||
Duan et al., 2020 | China | Nonrandomized, non-controlled study | 10 | 100% improved within 3 days | 1 evanescent facial red spot | [20] | ||
Li et al., 2020 | China | Randomized, controlled study | 53 | 51 | 51.9% improved within 28 days | 41.1% improved within 28 days | 2 adverse events within hours after transfusion | [28] |
Perotti et al., 2020 | Italy | Nonrandomized, non-controlled study | 46 | 6.5% died within 7 days | 5 serious adverse events | [26] | ||
Salazar et al., 2020 | US | Nonrandomized, non-controlled study | 25 | 76% improved within 14 days | None | [25] | ||
Shen et al., 2020 | China | Nonrandomized, non-controlled study | 5 | 100% improved | None | [21] | ||
Zeng et al., 2020 | China | Nonrandomized, non-controlled study | 6 | 15 | 83% died | 93% died | None | [24] |
Zhang et al., 2020 | China | Nonrandomized, non-controlled study | 4 | 100% improved | None | [22] |
COVID-19, coronavirus disease 2019.