Table 2.
Complete blood count (CBC) results 24 h after injection. Values of complete blood count (CBC) components 24 h after the first injection, displaying only mild thrombocytopaenia in S. elongatus rats but profound thrombocytopaenia, neutrophilia and lymphopaenia in LPS rats. Baseline values represent the mean ± SEM across all groups prior to the first injection.
| CBC findings | Baseline values | Saline | S. elongatus | LPS |
|---|---|---|---|---|
| Platelet count (platelets μl−1) | 913 000 ± 29 000 | 869 000 ± 29 000 | 728 000 ± 33 000** | 328 000 ± 33 000**** |
| White blood cell count (cells μl−1) | 9130 ± 490 | 11 000 ± 870 | 11 300 ± 880 | 10 600 ± 1000 |
| Neutrophil (%) | 15.0 ± 1.1 | 18.1 ± 1.3 | 20.8 ± 2.8 | 73.3 ± 4.5** |
| Lymphocyte (%) | 77.7 ± 1.3 | 77.3 ± 1.4 | 75.1 ± 2.9 | 24.5 ± 4.8** |
| Monocyte (%) | 5.93 ± 0.52 | 3.70 ± 0.73 | 3.80 ± 0.73 | 2.00 ± 0.41 |
| Eosinophil (%) | 1.33 ± 0.23 | 0.917 ± 0.29 | 0.417 ± 0.19 | 0.250 ± 0.25 |
LPS, lipopolysaccharide.
*
Significant vs. saline (P < 0.05), **significant vs. saline (P < 0.01), ***significant vs. saline (P < 0.001), ****significant vs. saline (P < 0.0001).