. 2020 Sep 14;21(5):e78. doi: 10.4142/jvs.2020.21.e78

Table 3. Gene ontology functional classification of genes that are differentially expressed at the effector site.

Item	No.	Gene
Inflammatory response	7	↑: CCL4. IL-1A. IL-6. IL-1B. SAA2
Inflammatory response	7	↓: C3. C5
Complement and coagulation cascades	7	↑: THBD. PROC
Complement and coagulation cascades	7	↓: C3. C5. C6. C8A. C9
Defense response	8	↑: CCL4. IL1A. IL-6. IL-1B. SAA2
Defense response	8	↓: C3. C5. IFNE
Toll-like receptor signaling pathway	7	↑: CD40. CD80. CCL5. CXCL10. CXCL9. IL-6. IL-1B
Cytokine-cytokine receptor interaction	10	↑: CD40. CCL4. CCL5. CCR3. CXCL10. CXCL9. IL-1A. IL-6. IL-1B
Cytokine-cytokine receptor interaction	10	↓: IFNE

p < 0.05 compared to uninfected sample of piglet.